Hydroanthracene based compounds as anticancer agents

Details Hydroanthracene based compounds as anticancer agents Hydroanthracene based compounds as anticancer agents

C - Chemistry, Metallurgy

07

C

C07C 43/23 (2006.01) A61P 35/00 (2006.01) C07C 49/755 (2006.01) C07C 50/34 (2006.01) C07C 50/38 (2006.01) C07C 69/145 (2006.01) C07C 69/157 (2006.01) C07C 229/34 (2006.01) C07C 251/44 (2006.01) C07C 271/22 (2006.01) C07D 239/30 (2006.01) C07D 263/06 (2006.01)

Patent

CA 2523019

The invention relates to the use of novel anthracene based compounds for the inhibition or prevention of the growth or multiplication of cancer cells, and to therapeutic compositions containing such compounds.The invention relates more specifically to the use of hydroanthracene based compounds for the inhibition and/or prevention of cancer of the colon, pancreas, prostate, lung, larynx, ovary, breast, glioblastoma, oral cavity, endothelial cells and leukemias. The agents of the invention form a distinct class, distinct from the anthracene, anthrone or anthraquinone derivatives.

L'invention se rapporte à l'utilisation de nouveaux composés à base d'anthracène servant à inhiber ou à prévenir la croissance ou la multiplication de cellules cancéreuses, ainsi qu'à des compositions thérapeutiques contenant lesdits composés. Cette invention concerne de manière plus spécifique l'utilisation de composés à base d'hydroanthracène pour inhiber et/ou prévenir le cancer du colon, du pancréas, de la prostate, du poumon, du larynx, de l'ovaire, du sein, de la cavité buccale et des cellules endothéliales, ainsi que les glioblastomes et les leucémies. Les agents selon l'invention forment une classe à part, distincte des dérivés d'anthracène, d'anthrone ou d'anthraquinone.

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