Hydrobenzamide derivatives as inhibitors of hsp90

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 209/44 (2006.01) A61K 31/496 (2006.01) A61P 35/00 (2006.01) C07C 65/28 (2006.01) C07C 69/92 (2006.01) C07C 235/60 (2006.01)

Patent

CA 2665931

The invention provides an acid addition salt of a compound of the formula (1) Also provided by the invention are processes for preparing the compound of formula (1) and alkyl analogues thereof, novel intermediates for use in the process and methods for preparing the intermediates. The invention also provides new medical uses of compounds of the formula (1) and its ethyl analogue.

L'invention concerne un sel d'addition avec un acide d'un composé de formule (1). L'invention concerne également des procédés servant à préparer le composé de formule (1) et des analogues alkyliques de celui-ci, de nouveaux intermédiaires destinés à être utilisés dans le procédé et des procédés servant à préparer les intermédiaires. L'invention concerne également de nouvelles utilisations médicales de composés de formule (1) et d'analogues éthyliques de ceux-ci.

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