Hydrogel compositions with an erodible backing member

A - Human Necessities – 61 – K

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A61K 9/70 (2006.01) A61K 9/14 (2006.01)

Patent

CA 2538727

A composition is provided, wherein the composition comprises a water- swellable, water-insoluble polymer and a blend of a hydrophilic polymer with a complementary oligomer capable of hydrogen or electrostatic bonding to the hydrophilic polymer. The composition also includes a backing member. Active ingredients, such as a whitening agent, may be included. The composition finds utility as an oral dressing, for example, a tooth whitening composition that is applied to the teeth in need of whitening. The composition can be designed to be removed when the degree of whitening has been achieved or left in place and allowed to erode entirely. In certain embodiments, the composition is translucent. Methods for preparing and using the compositions are also disclosed.

L'invention concerne une composition contenant un polymère gonflable dans l'eau et insoluble dans l'eau, et un mélange fait d'un polymère hydrophile et d'un oligomère complémentaire à liaison hydrogène ou électrostatique avec le polymère hydrophile. La composition comprend également un élément de support. La composition peut également comprendre des ingrédients actifs, par exemple un agent de blanchiment. Cette composition est utilisée par voie orale, par exemple dans une composition de blanchiment des dents appliquée sur des dents nécessitant d'être blanchies. La composition peut être retirée lorsque le degré de blanchiment est atteint ou maintenue jusqu'à ce qu'elle se dégrade entièrement. Dans certains modes de réalisation, la composition est translucide. L'invention concerne également des procédés de préparation et d'utilisation de ces compositions.

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