C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/34 (2006.01) A61K 31/445 (2006.01) A61K 31/4523 (2006.01) A61K 31/4525 (2006.01) A61K 31/4535 (2006.01) A61K 31/454 (2006.01) A61P 3/00 (2006.01) A61P 35/00 (2006.01) C07D 211/96 (2006.01) C07D 401/06 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01) C07D 409/14 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2600528
Compounds of structure (I) having histone deacetylase (HDAC) inhibitor activity are described. The compounds are chemically characterised by the presence of hydroxamic acid, with zinc as chelator, and an aromatic nucleus connected by a linker in which either a bicyclic aromatic system or a piperidino ring are present.
L'invention concerne des composés ayant la structure (I) ayant une activité d'inhibiteurs d'hystone désacétylase (HDAC). Les composés sont caractérisés chimiquement par la présence d'acide hydroxamique, le zinc étant utilisé comme chélateur, et par un noyau aromatique connecté par un lieur dans lequel est présent soit un système aromatique bicyclique soit un anneau pipéridino.
D'andrea Piero
Fattori Daniela
Marastoni Elena
Porcelloni Marina
Rossi Cristina
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Menarini International Operations Luxembourg S.a.
LandOfFree
Hydroxamates as histone deacetylase inhibitors and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Hydroxamates as histone deacetylase inhibitors and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hydroxamates as histone deacetylase inhibitors and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2080564