Hydroxylated inhibitors of hiv reverse transcriptase

Details Hydroxylated inhibitors of hiv reverse transcriptase Hydroxylated inhibitors of hiv reverse transcriptase

C - Chemistry, Metallurgy

12

P

C12P 17/16 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 213/74 (2006.01) C07D 401/02 (2006.01) C07D 401/12 (2006.01) C07D 405/02 (2006.01) C07D 409/02 (2006.01) C07D 413/02 (2006.01) C07D 413/12 (2006.01) C07D 417/02 (2006.01) C07D 498/04 (2006.01) C12P 17/12 (2006.01)

Patent

CA 2053512

155/RDM80 156/RDM81 18212Y TITLE OF THE INVENTION HYDROXYLATED INHIBITORS OF HIV REVERSE TRANSCRIPTASE ABSTRACT OF THE DISCLOSURE Novel biotransformed or synthetic hydroxy pyridinones inhibit HIV reverse transcriptase, and are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts (where appropriate), pharmaceutical composition ingredients, whether or not in combination with other antivirals, anti-infectives, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

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