Identification of genes implicated in the virulence of...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/195 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2654968

Group B streptococcus is an important cause of maternal and neonatal morbidity and mortality in many part of the world. The invention is a method of identification of novel targets for inhibitors preventing septicemic dissemination of Streptococcus agalactiae, a model of Gram positive bacteria, in order to treat bacterial infections using these virulence determinant.

La présente invention concerne le streptocoque du groupe B, cause importante de morbidité et de mortalité maternelle et néonatale dans de nombreuses régions du monde. L'invention concerne un procédé d'identification de cibles innovantes pour des inhibiteurs qui évitent la dissémination septicémique d'un modèle de bactérie Gram positive, Streptococcus agalactiae, dans le but de traiter les infections bactériennes en utilisant ces déterminants de la virulence.

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