Il-17 antagonistic antibodies

Details Il-17 antagonistic antibodies Il-17 antagonistic antibodies

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61P 29/00 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2573586

An IL-17 binding molecule, in particular an antibody to human IL-17, more preferably a human antibody to IL-17 is provided, wherein the hypervariable regions of the heavy and light chains have amino acid sequences as defined, for use in the treatment of an IL-17 mediated disease or disorder, e.g. rheumatoid arthritis.

Cette invention concerne une molécule de liaison de l'IL-17, en particulier un anticorps de l'IL-17 humain, mieux encore un anticorps humain de l'IL-17, dont les régions hypervariables des chaînes lourdes et légères présentent des séquences d'acides aminés comme indiqué dans le descriptif, et qui dont l'utilisation convient pour le traitement des maladies ou des troubles induits par IL-17 tels que la polyarthrite rhumatoïde..

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