Imidazopyrazine as tyrosine kinase inhibitors

Details Imidazopyrazine as tyrosine kinase inhibitors Imidazopyrazine as tyrosine kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/53 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2574594

Compounds of the formula (I): and pharmaceutically acceptable salts thereof, wherein Q1 and R1 are defined herein, inhibit the IGF- 1 R enzyme and are useful for the treatment and/or prevention of various diseases and conditions that respond to treatment by inhibition of tyrosine kinases.

L'invention concerne des composés de la formule (I) et des sels pharmaceutiquement acceptables de ceux-ci, dans lesquels Q1 et R1 sont définis dans le descriptif, inhibent l'enzyme IGF-1R et sont utilisés dans le traitement et/ou la prévention de maladies et états divers qui réagissent au traitement par inhibition des tyrosine kinases.

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