Imidazopyrazines as protein kinase inhibitors

Details Imidazopyrazines as protein kinase inhibitors Imidazopyrazines as protein kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/498 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2628455

In its many embodiments, the present invention provides a novel class of imidazopyrazine compounds as inhibitors of protein and/or checkpoint kinases, methods of preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of preparing pharmaceutical formulations including one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the protein or checkpoint kinases using such compounds or pharmaceutical compositions.

La présente invention concerne une nouvelle classe de composés d~imidazopyrazine inhibant une protéine et/ou un checkpoint kinases, des procédés de préparations de tels composés, des compositions pharmaceutiques renfermant un ou plusieurs de ces composés, des procédés de préparation de formulations pharmaceutiques renfermant un ou plusieurs de ces composés et des méthodes de traitement, de prévention, d~inhibition ou d~amélioration d~une ou de plusieurs des maladies associées à la protéine ou au checkpoint kinases, qui utilisent ces composés ou compositions pharmaceutiques.

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