Immortalized and malignant human prostatic cell lines

Details Immortalized and malignant human prostatic cell lines Immortalized and malignant human prostatic cell lines

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) C12N 5/06 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2187088

Immortalized malignant human prostatic epithelial and fibroblast cell lines containing DNA of a human papillomavirus (HPV) and similar cell lines containing DNA of a human papillomavirus and an activated viral ras oncogene such as v-Ki-ras. The cell lines are useful for research on drugs for treatment of prostatic cancer and other diseases. The cell lines are useful for research on causes, treatment and prevention of prostate cancer, benign prostatic hyperplasia, male infertility, birth defects, aging and assessment of environmental toxic agents.

Lignées cellulaires de fibroblastes et épithéliales prostatiques humaines malignes immortalisées qui contiennent de l'ADN d'un papillomavirus humain (HPV) et lignées cellulaires similaires contenant de l'ADN d'un papillomavirus humain et un oncogène ras viral activé, tel que v-Ki-ras. Lesdites lignées cellulaires sont utiles pour la recherche sur des médicaments destinés au traitement du cancer de la prostate et d'autres maladies. Elles sont en outre utiles pour la recherche sur les causes, le traitement et la prévention du cancer de la prostate, de l'adénome prostatique, de l'infertilité masculine, des anomalies congénitales, du vieillissement, ainsi que pour l'évaluation d'agents toxiques présents dans l'environnement.

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