Immunization against endogenous molecules

A - Human Necessities – 61 – K

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Details

A61K 39/00 (2006.01) A61K 39/385 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2279826

A method is described for immunoneutralization of endogenous molecules in mammalian subjects, wherein an immunogen is administered via injection to the ear. The method is used to elicit an efficient and uniform immune response sufficient to block or suppress the activity of an endogenous hormone in a vaccinated subject, or to target a diseased cell for an immune response.

Cette invention se rapporte à un procédé permettant de réaliser l'immunoneutralisation de molécules endogènes chez des sujets mammifères, procédé dans lequel un immunogène est administré par injection dans l'oreille. Ce procédé est utilisé pour déclencher une réponse immunitaire efficace et uniforme, suffisante pour bloquer ou supprimer l'activité d'une hormone endogène chez un sujet vacciné ou pour cibler une cellule malade en vue d'une réponse immunitaire.

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