Immunogenic composition for use in vaccination against...

A - Human Necessities – 61 – K

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A61K 39/085 (2006.01) A61K 39/116 (2006.01) A61P 31/04 (2006.01) C07K 16/12 (2006.01)

Patent

CA 2580103

The present application relates to immunogenic compositions comprising a mixture of staphylococcal antigens which combines antigen having different functions, for instance, combinations including a staphylococcal extracellular component binding protein and a staphylococcal transporter protein or a staphylococcal extracellular component binding protein and a staphylococcal regulator of virulence or toxin or a staphylococcal transporter protein and a staphylococcal regulator of virulence or toxin. Vaccines, methods of treatment, uses of and processes to make a staphylococcal vaccine are also described.

L'invention concerne des compositions immunogènes comprenant un mélange d'antigènes staphylococciques, lequel mélange combine un antigène ayant différentes fonctions, par exemple, des combinaisons comportant une protéine de liaison de composant extra-cellulaire staphylococcique et une protéine de transport staphylococcique, ou une protéine de liaison de composant extra-cellulaire staphylococcique et un régulateur staphylococcique de virulence ou de toxine, ou bien une protéine de transport staphylococcique et un régulateur staphylococcique de virulence ou de toxine. La présente invention porte également sur des vaccins, sur des méthodes de traitement, sur des applications et des procédés pour réaliser un vaccin staphylococcique.

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