Immunological tolerance-inducing agent

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/385 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2173254

An immunological tolerance-inducing agent comprising a mucosabinding molecule linked to a specific tolerogen is disclosed. Further, a method of inducing immunological tolerance in an individual against a specific antigen, including hapten, which causes an unwanted immune response in said individual comprising administration by a mucosal route of an immunologically effective amount of an immunological tolerance-inducing agent of the invention to said individual, is described.

Agent d'induction d'immunotolérance, comportant une molécule de liaison aux muqueuses liée à un tolérogène spécifique. On a également prévu un procédé d'induction chez un individu de l'immonotolérance vis-à-vis d'un antigène spécifique, notamment l'haptène, qui provoque chez ledit individu une réponse immunitaire indésirable, ledit procédé consistant à administrer par voie muqueuse une quantité à efficacité immunologique d'un agent d'induction d'immunotolérance du type précité.

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