Immunomodulating compositions and uses therefor

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2604242

The present invention discloses the use of an inhibitor of IL-10 function and an immune stimulator that stimulates the priming of an immune response to a target antigen, in methods and compositions for stimulating and prolonging host immune responses to the target antigen. The methods and compositions of the present invention are particularly useful in the treatment or prophylaxis of a range of conditions including pathogenic infections and cancers.

La présente invention décrit l~utilisation d~un inhibiteur de la fonction IL-10 et d'un stimulateur immunitaire qui stimule l~amorçage d~une réponse immunitaire à un antigène cible, dans des procédés et des compositions pour stimuler et prolonger les réponses immunitaires de l~hôte à l~antigène cible. Les procédés et compositions de la présente invention sont particulièrement utiles dans le traitement ou la prophylaxie d~une gamme de conditions comprenant les infections pathogènes et les cancers.

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