C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/30 (2006.01) A61K 31/70 (2006.01) A61K 31/7032 (2006.01) A61K 31/739 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) C07K 16/00 (2006.01) C07K 16/18 (2006.01) C07K 16/42 (2006.01) C12N 5/20 (2006.01)
Patent
CA 2443372
The invention relates to the field of immunology and specifically to immunotherapeutic combinations that are used to impede the growth of tumour cells and/or to eliminate said cells. The present invention can be used to observe a therapeutic antitumour effect by combining idiotypic vaccines having an antiganglioside antibody (Ab1) as the active principle thereof with idiotypic vaccines, the active principle of which is an anti-idiotype antibody obtained against an antiganglioside antibody (Ab2), or with vaccines, the active principle of which is one or more gangliosides. The invention relates to combinations of said vaccines which produce a synergism of the antitumour effect which is induced separately by each of the vaccines. Said combinations can be applied to patients in different clinical states with tumours that overexpress gangliosides.
La présente invention concerne le domaine de l'immunologie et, en particulier, des combinaisons immunothérapeutiques utilisées pour empêcher la croissance des cellules tumorales et/ou éliminer lesdites cellules. La présente invention permet d'observer un effet thérapeutique antitumoral par la combinaison de vaccins idiotypiques dont le principe actif est un anticorps antiganglioside (Ab1), avec des vaccins idiotypiques dont le principe actif est un anticorps anti-idiotype obtenu contre un anticorps antiganglioside (Ab2), ou avec des vaccins dont le principe actif est un ou plusieurs gangliosides. L'invention concerne des combinaisons de ces vaccins qui provoquent un synergisme de l'effet anti-tumoral induit séparément par chacun des vaccins. Lesdites combinaisons peuvent s'appliquer à des patients à différents stades cliniques de tumeurs surexprimant les gangliosides.
Alfonso Fernandez Mauro A.
Carr Perez Adriana
Diaz Rodriguez Yildian
Fernandez Molina Luis Enrique
Perez Gonzalez Alexis
Alfonso Fernandez Mauro A.
Carr Perez Adriana
Centro de Inmunologia Molecular
Diaz Rodriguez Yildian
Fernandez Molina Luis Enrique
LandOfFree
Immunotherapeutic combinations for the treatment of tumors... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Immunotherapeutic combinations for the treatment of tumors..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immunotherapeutic combinations for the treatment of tumors... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1956716