Improved raf inhibitors

Details Improved raf inhibitors Improved raf inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/505 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2722020

The present invention provides derivatives of pyrido[2,3-d]pyrimidin-7-one. These compounds are inhibitors or kinases such as Raf, including compounds that show anti-proliferative activity, including against tumor cells, and are useful in the treatment of diseases including cancer.

La présente invention concerne des dérivés de pyrido[2,3-d]pyrimidin-7-one. Ces composés sont des inhibiteurs de kinases telles que Raf, y compris des composés qui présentent une activité antiproliférative, y compris contre des cellules tumorales et ils sont utiles dans le traitement de maladies y compris le cancer.

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