Indoles, derivatives, and analogs thereof and uses thereof

Details Indoles, derivatives, and analogs thereof and uses thereof Indoles, derivatives, and analogs thereof and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 209/12 (2006.01) A61K 31/404 (2006.01) A61P 35/00 (2006.01) C07D 209/08 (2006.01) C07D 209/10 (2006.01) C07D 209/14 (2006.01) C07D 209/18 (2006.01) C07D 401/00 (2006.01) C07D 403/14 (2006.01) C07D 405/06 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2707238

Indole derivatives and analog compounds and pharmaceutical compositions comprising the same are provided. Also provided are methods of using these compounds to inhibit tubulin polymerization in a cell associated with a proliferative dis-ease or to treat a cancer.

L'invention concerne des dérivés d'indoles et des composés analogues et des compositions pharmaceutiques les comprenant. L'invention concerne également des procédés d'utilisation de ces composés pour inhiber la polymérisation de la tubuline dans une cellule associée avec une maladie proliférative ou pour traiter un cancer.

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