Indoles useful in the treatment of inflammation

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 209/42 (2006.01) A61K 31/404 (2006.01) A61P 11/00 (2006.01) A61P 29/00 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2594878

There is provided compounds of formula (I), Wherein X1 , R1 , R2 , R3, R4, R5 and R6 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.

La présente invention concerne des composés de formule (I), où X1, R1,R2 R3, R4, R5 et R6 ont des significations fournies dans la description, ainsi que des sels pharmaceutiquement acceptables de ceux-ci; lesdits composés sont utiles dans le traitement des maladies pour lesquelles l'inhibition de l'activité d'un membre de la famille des MAPEG est souhaitée et/ou nécessaire, en particulier dans le traitement de l'inflammation.

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