C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/42 (2006.01) A61K 31/404 (2006.01) A61P 29/00 (2006.01) C07D 401/04 (2006.01)
Patent
CA 2570363
There is provided a compound of formula: (I), wherein X, R1, R2, R3, R4, R5 and R6 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation.
Un composé de formule (I), dans laquelle X, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿ et R?6¿ sont tels que définis dans la description et ses sels pharmaceutiquement acceptables. Les composés sont utilisés dans le traitement de maladies nécessitant l'inhibition de l'activité de la prostaglandine E synthase-1 microsomale et plus particulièrement dans le traitement d'inflammations.
Kalvins Ivars
Katkevics Martins
Olofsson Kristofer
Ozola Vita
Pelcman Benjamin
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Biolipox Ab
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