C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/42 (2006.01) A61K 31/404 (2006.01) A61P 29/00 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01)
Patent
CA 2570365
There is provided a compound of formula (I), wherein X, R1, R2, R3, R4, R5 and R6 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation.
L'invention concerne un composé de la formule (I) où X, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿ et R?6¿ ont la signification donnée dans la description, et leurs sels pharmaceutiquement acceptables, ces composés étant utiles dans le traitement de maladies dans lesquelles l'inhibition de l'activité de la prostaglandine E synthase-1 microsomale est souhaitée et/ou exigée, et notamment dans le traitement de l'inflammation.
Kalvins Ivars
Katkevics Martins
Olofsson Kristofer
Ozola Vita
Pelcman Benjamin
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Biolipox Ab
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