Indolyl-urea derivatives of thienopyridines useful as...

Details Indolyl-urea derivatives of thienopyridines useful as... Indolyl-urea derivatives of thienopyridines useful as...

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/4365 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2478050

The invention relates to compounds represented by the formula FI and to prodrugs thereof, pharmaceutically acceptable salts or solvates of said compounds or said prodrugs, wherein X, R1 and R11 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula I.

L'invention concerne des composés représentés par la formule générale (I), des promédicaments de ces composés, ainsi que des sels de qualité pharmaceutique ou des solvates de ces composés ou de ces promédicaments. Dans cette formule générale (I), X, R?1¿ et R?11¿ désignent des éléments définis dans le descriptif de la présente demande. L'invention concerne également des compositions pharmaceutiques renfermant les composés représentés par la formule générale (I), ainsi que des méthodes destinées au traitement de troubles hyperprolifératifs chez un mammifère, consistant à administrer lesdits composés.

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