Inducing cellular immune responses to her2/neu using peptide...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/00 (2006.01) A61K 38/03 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 39/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 7/00 (2006.01) C07K 9/00 (2006.01) C07K 14/435 (2006.01) C07K 14/71 (2006.01)

Patent

CA 2393738

This invention uses our knoeledge of the mechanisms by which antigen is recognized by T cells to identify and prepare HER2/neu epitopes, and to develop epitope-based vaccines directed towards HERS2/neu-bearing tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of cancer.

L'invention fait appel à nos connaissances des mécanismes par lesquels un antigène est reconnu par des lymphocytes T, pour identifier et préparer des épitopes HER2/neu et pour mettre au point des vaccins sur la base de ces épitopes dirigés contre les tumeurs contenant HER2/neu. Plus précisément, cette demande concerne la découverte de compositions pharmaceutiques et leurs méthodes d'utilisation dans la prévention et le traitement du cancer.

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