Inducing cellular immune responses to mage2/3 using peptide...

Details Inducing cellular immune responses to mage2/3 using peptide... Inducing cellular immune responses to mage2/3 using peptide...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 35/08 (2006.01) A61K 38/04 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 7/00 (2006.01) C07K 9/00 (2006.01) C07K 11/00 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2393339

The invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare MAGE2/3 epitopes, and to develop epitope-based vaccines directed towards MAGE2/3-bearing tumors. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of cancer.

L'invention utilise nos connaissances des mécanismes par lesquels l'antigène est reconnu par les lymphocytes T pour identifier et préparer des épitopes MAGE2/3, et pour développer des vaccins à base d'épitopes, ciblés sur des tumeurs porteuses de MAGE2/3. Plus spécialement, l'invention concerne des compositions pharmaceutiques et leurs procédés d'utilisation dans la prévention et le traitement du cancer.

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