C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/77 (2006.01) A61K 31/335 (2006.01) A61K 31/36 (2006.01) C07D 311/02 (2006.01) C07D 317/70 (2006.01) C07D 407/14 (2006.01) C07D 493/00 (2006.01) C07D 493/04 (2006.01)
Patent
CA 2341540
This invention relates to anti-viral drugs such as Helioxanthin and its analogs. The present compounds may be used alone or in combination with other drugs for the treatment of Hepatitis B virus (HBV), Hepatitis C virus (HCV), Yellow Fever, Dengue Virus, Japanese Encephalitis, West Nile virus and related flaviriruses. In addition, compounds according to the present invention can be used to prevent hepatoma secondary to virus infection as well as other infections or disease states which are secondary to the virus infection.
La présente invention concerne des médicaments antiviraux tels que l'hélioxanthine et ses analogues. Les composés selon l'invention peuvent être utilisés seuls ou combinés avec d'autres médicaments pour combattre les virus de l'hépatite B (HBV), de l'hépatite C (HCV), de la fièvre jaune, de la dengue, de l'encephalite japonaise, West Nile et autres flavivirus. De plus, ces composés peuvent être utilisés pour prévenir un carcinome hépatocellulaire secondaire à une infection virale ainsi que d'autres infections ou états pathologiques faisant suite à une infection virale.
Cheng Yung-Chi
Chou Chen-Kung
Fu Lei
Kuo Yueh-Hsiung
Yeh Sheau-Farn
Cassan Maclean
National Taiwan University
National Yang Ming University
Veterans General Hospital
Yale University
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