Inhibition of emetic effect of metformin with 5-ht3 receptor...

A - Human Necessities – 61 – K

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A61K 31/46 (2006.01) A61K 31/155 (2006.01) A61K 31/4178 (2006.01) A61K 31/439 (2006.01) A61K 45/06 (2006.01) A61P 1/08 (2006.01)

Patent

CA 2422711

Metformin is formulated as a pharmaceutical composition that also includes a 5- hydroxytryptamine-3 receptor antagonist to suppress the gastrointestinal side effects that are associated with metformin administration in many patients.

La metformine est formulée comme une composition pharmaceutique contenant aussi un antagoniste du récepteur 5-hydroxytryptamine-3 afin de supprimer les effets secondaires gastro-intestinaux qui sont associés à l'administration de la metformine chez de nombreux patients.

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