Inhibitors of checkpoint kinases

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/12 (2006.01) A61K 31/422 (2006.01)

Patent

CA 2610884

The instant invention provides for compounds which comprise substituted pyridyl aminothiazoles that inhibit CHK1 activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting CHK1 activity by administering the compound to a patient in need of treatment of cancer.

L'invention concerne des composés comprenant des pyridyl aminothiazoles substitués qui inhibent l'activité de CHK1. Elle concerne aussi des compositions comprenant de tels composés inhibiteurs, et des procédés visant à inhiber l'activité de CHK1 par l'administration du composé à un patient nécessitant un traitement anticancéreux.

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