C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/48 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2186987
The invention relates to methods for preventing or treating cardiomyopathy associated with diabetes mellitus and hyperglycemia by inhibiting core 2 GlcNAc-T; methods for screening for substances that affect cardiomyopathy associated with diabetes mellitus and hyperglycemia; and methods and pharmaceutical compositions containing the substances for preventing or treating cardiomyopathy associated with diabetes mellitus and hyperglycemia.
L'invention concerne des méthodes pour prévenir ou traiter la cardiomyopathie liée au diabète sucré et à l'hyperglycémie par inhibition de la « core 2 GlcNAc-T »; des méthodes de criblage des substances qui agissent sur la cardiomyopathie liée au diabète sucré et à l'hyperglycémie; et des méthodes et compositions pharmaceutiques contenant les substances pour prévenir ou traiter la cardiomyopathie liée au diabète sucré et à l'hyperglycémie.
Dennis James W.
King George L.
Koya Daleuke
Nishio Yoshihiko
Warren Charles E.
Bereskin & Parr
Dennis James W.
King George L.
Koya Daleuke
Mount Sinai Hospital Corporation
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