Inhibitors of factor xa

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 311/46 (2006.01) A61K 31/18 (2006.01) A61P 7/02 (2006.01) C07C 317/32 (2006.01) C07D 307/54 (2006.01) C07D 307/68 (2006.01) C07D 413/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2382751

The present application relates to compounds of the general formula A-Y-D-E-G- J-K-L, wherein A, Y, D, E, G, J, K and L have the meanings given in the description, having activity against mammalian factor Xa. The compounds are useful <i>in vitro</i> or <i>in vivo</i> for preventing or treating coagulation disorders.

L'invention concerne des composés représentés dans la formule générale A-Y-D-E-G-J-K-L, dans laquelle A-Y-D-E-G-J-K et L sont tels que décrits dans l'invention. Ces composés sont actifs contre le facteur Xa mammalien. Ces composés sont utilisés in vitro et in vivo pour prévenir ou traiter les troubles de la coagulation.

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