Inhibitors of farnesyl protein transferase

Details Inhibitors of farnesyl protein transferase Inhibitors of farnesyl protein transferase

C - Chemistry, Metallurgy

07

D

C07D 207/12 (2006.01) A61K 31/40 (2006.01) C07D 207/00 (2006.01) C07D 211/00 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2388669

This invention relates to compounds of formula (I) that inhibit farnesylation of gene products through inhibition of the enzyme farnesyl-protein transferase (FPTase). The invention also relates to methods of manufacturing the compounds, pharmaceutical compositions and methods of treating diseases, especially cancer, which are mediated through farnesylation.

L'invention concerne des composés de formule (I) qui inhibent la farnésylation de produits géniques par le biais de l'inhibition de l'enzyme farnésyl protéine transférase (FPTase). Elle concerne également des procédés de fabrication de ces composés, de compositions pharmaceutiques et de procédés de traitement de maladies, notamment le cancer, qui sont induites par la farnésylation.

Affiliated with

Also associated with

Rating

Inhibitors of farnesyl protein transferase does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Inhibitors of farnesyl protein transferase, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibitors of farnesyl protein transferase will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1733394