Inhibitors of farnesyl protein transferase

Details Inhibitors of farnesyl protein transferase Inhibitors of farnesyl protein transferase

C - Chemistry, Metallurgy

07

K

C07K 5/06 (2006.01) A61K 31/16 (2006.01) A61K 31/395 (2006.01) A61K 38/05 (2006.01) C07C 323/25 (2006.01) C07C 323/41 (2006.01) C07C 323/67 (2006.01) C07D 207/16 (2006.01) C07D 209/20 (2006.01) C07D 213/56 (2006.01) C07D 233/64 (2006.01) C07D 235/08 (2006.01)

Patent

CA 2137455

2137455 9400419 PCTABScor01 The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

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