Inhibitors of fatty acid amide hydrolase

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 5/02 (2006.01) A61K 31/69 (2006.01) A61P 29/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2721060

The present invention provides compounds, and pharmaceutically acceptable compositions thereof, encompassed by any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof. The present invention also provides methods for treating an FAAH mediated dis-ease, disorder or condition by administering a therapeutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof. Additionally, the present invention provides methods for in-hibiting FAAH by administering a thera-peutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof.

La présente invention concerne des composés et des compositions de qualité pharmaceutique de ceux-ci, qui sont inclus dans l'une quelconque des formules (I), (II), (III), (IV), (V) ou (VI), ou des sous-genres de celles-ci. L'invention concerne également des procédés pour traiter une maladie, un trouble ou un état à médiation par le FAAH en administrant une quantité thérapeutique, efficace d'un composé ou d'une composition comportant un composé de l'une quelconque des formules (I), (II), (III), (IV), (V) ou (VI), ou de sous-genres de celles-ci, à un patient en ayant besoin. De plus, la présente invention concerne des procédés pour inhiber le FAAH en administrant une quantité thérapeutique, efficace d'un composé ou d'une composition comportant un composé de l'une quelconque des formules (I), (II), (III), (IV), (V) ou(VI), ou des sous-genres de celles-ci, à un patient en ayant besoin.

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