Inhibitors of histone deacetylase

Details Inhibitors of histone deacetylase Inhibitors of histone deacetylase

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/16 (2006.01) A61K 31/41 (2006.01) A61K 31/428 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/472 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07C 233/44 (2006.01) C07C 233/80 (2006.01) C07C 235/38 (2006.01) C07C 235/42 (2006.01) C07C 235/56 (2006.01) C07C 235/84 (2006.01) C07C 237/20 (2006.01) C07C 237/22 (2006.01) C07C 237/40 (2006.01) C07C 237/42 (2006.01) C07C 255/58 (2006.01) C07C 255/59 (2006.01) C07C 275/34 (2006.01) C07C 275/36 (2006.01) C07C 311/42

Patent

CA 2465978

The invention relates to the inhibition of histone deacetylase. The invention provides compounds e.g. (1) and methods for inhibiting deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions. (formula 1). All definitions are as the application.

L'invention concerne l'inhibition de l'histone-déacétylase, ainsi que des composés et des procédés d'inhibition de l'activité enzymatique de l'histone-déacétylase. L'invention concerne également des compositions et des méthodes de traitement de maladies et d'états liés à la prolifération cellulaire.

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