Inosine derivatives and production methods therefor

Details Inosine derivatives and production methods therefor Inosine derivatives and production methods therefor

C - Chemistry, Metallurgy

07

H

C07H 19/167 (2006.01) A61K 31/522 (2006.01) A61K 31/708 (2006.01) A61P 31/18 (2006.01) C07D 473/30 (2006.01) C07H 19/16 (2006.01)

Patent

CA 2727748

The present invention provides a method for producing an inosine derivative represented by the following general formula (1) including the steps of subjecting an inosine derivative of general formula (3) to dithiocarbonylation and carrying out radical reduction of the obtained compound. According to the present invention there can be produced compounds useful as anti-AIDS drugs on industrial scale. (see formula 1)(see formula 3) wherein R1 may be the same or different and are each benzyl group, benzhydryl group or trityl group, each of which may have a substituent in general formulas (1) and (3).

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