Insecticidal toxins, genes encoding these toxins, antibodies...

C - Chemistry – Metallurgy – 12 – N

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167/139, 167/5.1

C12N 15/12 (2006.01) A01H 5/00 (2006.01) A01N 37/18 (2006.01) A01N 43/36 (2006.01) A01N 43/50 (2006.01) A01N 63/00 (2006.01) A01N 63/02 (2006.01) C07K 14/435 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2005658

Case 5-17404/5/6/CGC 1388/9/0 Insecticidal toxins. genes encoding these toxins. antibodies binding to them and transgenic plant cells and plants expressing these toxins Abstract This invention relates to transgenic plants, plant cells and microorganisms which by use of recombinant DNA technology have been so transformed that they are capable of synthesizing insect selective toxins from venoms of venomous animals preferably members of the phylum Arthropoda, more preferably of members of the class Arachnida, most preferably of members of the order Scorpiones, and more preferably of members of the class Chilopoda. The invention further relates to genes encoding said insect selective toxins and the use of said genes to confer to plants a genetically mediated resistance to insects and to control phytopathogenic insects. The invention also relates to a toxin from the venom of the Scorpion Leiurus quinquestriatus hebraeus with the amino acid sequence Image The invention further relates to antibodies for said toxins and insecticidally effective compositions comprising said toxins.

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