Insoluble drug delivery

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/16 (2006.01) A61K 31/235 (2006.01) A61K 31/405 (2006.01) A61K 38/13 (2006.01)

Patent

CA 2234957

Particles of water insoluble biologically active compounds, particularly water- insoluble drugs, with an average size of 100 nm to about 300 nm, are prepared by dissolving the compound in a solution then spraying the solution into compressed gaz, liquid or supercritical fluid in the presence of appropriate surface modifiers.

Particules de composés biologiquement actifs non hydrosolubles, en particulier de médicaments non hydrosolubles, dont la taille moyenne varie entre 100 nm et environ 300 nm, qui sont préparés par dissolution du composé dans une solution, puis par pulvérisation de ladite solution dans du gaz, du liquide ou du fluide surcritique sous pression, en présence de modificateurs de surface appropriés.

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