C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/25 (2006.01) A61K 38/20 (2006.01) C07K 14/54 (2006.01) C07K 14/545 (2006.01) C07K 16/24 (2006.01) C12N 5/12 (2006.01) C12N 15/24 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2395417
The present invention provides novel Interleukin-1 Receptor Antagonist-Related (IL-1ra-R) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing IL-1ra-R polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with IL-1ra-R polypeptides.
L'invention concerne des polypeptides liés à l'antagoniste du récepteur de l'interleukine-1 (IL-1ra-R) et des molécules d'acide nucléique codant pour ces polypeptides. L'invention concerne également des agents de liaison, des vecteurs, des cellules hôtes sélectifs ainsi que des méthodes de production de polypeptides IL-1ra-R. L'invention concerne des compositions pharmaceutiques ainsi que des méthodes permettant de diagnostiquer, d'améliorer le traitement et/ou de prévenir des maladies, des troubles et des états pathologiques associés aux polypeptides IL-1ra-R.
Bass Michael Brian
Craveiro Roger
Giles Jennifer
Mu Sharon X.
Saris Christiaan M.
Amgen Inc.
Gowling Lafleur Henderson Llp
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