C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/312, 260/304
C07D 257/04 (2006.01) C07D 405/06 (2006.01) C07F 9/547 (2006.01) C07F 9/6524 (2006.01)
Patent
CA 1328269
ABSTRACT This invention provides novel tetrazole intermediates of the formula Image wherein R1 and R4 each are independently hydrogen, halogen, C1-4 alkyl, C1-4 alkoxy or trifluoro- methyl; R2, R3, R5 and R6 each are independently hydrogen, halogen, C1-4 alkyl or C1-4 alkoxy; B is hydrogen, C1-4 alkoxycarbonyl, CH2Y or CH2Z; Y is hydrogen, hydroxyl or X; Z is Image or Image ; X is bromo, chloro or iodo; R10 is C1-4 alkyl; and R11 is phenyl which is unsubstituted or substituted by one or two C1-4 alkyl or chloro substituents. and processes thereof which are useful for the preparation of antihypercholesterolemic agents.
559671
Balasubramanian Neelakantan
Brown Peter J.
Sit Sing-Yuen
Wright John J.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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