Internallly administered therapeutic agents for diseases in...

A - Human Necessities – 61 – K

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A61K 35/28 (2006.01) A61K 35/14 (2006.01) A61K 35/34 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2535034

By collecting bone marrow cells from rat bone marrow and intravenously administering the cells to a brain infarction model rat, it is found out that these cells are efficacious in treating brain infarction. It is also found out that human and mouse bone marrow stem cells have the same effect. Namely, mesenchymal cells such as bone marrow cells, umbilical cord blood cells or peripheral blood cells are usable as a drug for intravenous administration against cranial nerve diseases.

Le prélèvement de cellules de moelle osseuse de rat et l'administration par voie intraveineuse de ces cellules à un rat modèle d'infarctus cérébral ont permis d'établir que ces cellules sont efficaces pour traiter l'infarctus cérébral. On a également pu établir que les cellules souches de moelle osseuse humaine et de rat avaient le même effet. L'invention concerne l'utilisation de cellules mésenchymateuses telles que des cellules de moelle osseuse, des cellules sanguines de cordon ombilical ou des cellules de sang périphérique, comme médicament s'administrant par voie intraveineuse et destiné à traiter des maladies des nerfs crâniens.

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