Intracellular signaling molecules

Details Intracellular signaling molecules Intracellular signaling molecules

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) C07K 1/14 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/12 (2006.01) C12N 15/11 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2449272

Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.

Plusieurs aspects de l'invention portent sur des molécules intracellulaires de signalisation humaines (INTSIG) et sur des polynucléotides identifiant les INTSIG et codant pour elles. Certains aspects portent sur des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes, et des antagonistes, et d'autres aspects, sur des méthodes de diagnostic, de traitement ou de prévention de troubles liés à l'expression aberrante des INTSIG.

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