Intracutaneous edged microneedle structure

A - Human Necessities – 61 – M

Patent

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Details

A61M 37/00 (2006.01)

Patent

CA 2376286

A hollow microneedle with a substantially sharp edge is provided that includes at least one longitudinal blade at the top surface or tip of the microneedle to aid in penetration of the stratum corneum of skin. The blade's edge can run the entire length of the microneedle from its very top surface to its bottom surface where it is mounted onto the substrate, or the edge can be discontinued partway down the length of the microneedle. In a preferred embodiment, a three pointed star-shape is used, in which each blade has an isosceles triangular cross-section when viewed from the top of the microneedle. At least one hole through the substrate is located near the side surfaces of the pairs of blades of the solid microneedle.

L'invention concerne une micro-aiguille creuse comportant un bord sensiblement effilé qui comprend au moins une lame longitudinale à la surface supérieure ou à la pointe de la micro-aiguille, qui facilite la pénétration dans la couche cornée de l'épiderme. Le bord de la lame peut s'étendre sur toute la longueur de la micro-aiguille, depuis le tout début de sa structure jusqu'au fond de celle-ci, où il est monté sur un substrat, ou être interrompu sur une partie de la longueur de la micro-aiguille. Dans un mode de réalisation préféré, on utilise la forme d'une étoile à trois branches, chaque lame vue depuis le haut de la micro-aiguille se présentant en coupe comme un triangle isocèle. Au moins un trou traversant le substrat est disposé près des surfaces latérales des paires de lames de la micro-aiguille solide.

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