Isomers of 1-azabicyclo¬2.2.2|oct-3-yl...

Details Isomers of 1-azabicyclo¬2.2.2|oct-3-yl... Isomers of 1-azabicyclo¬2.2.2|oct-3-yl...

C - Chemistry, Metallurgy

07

D

167/231, 260/272

C07D 453/02 (2006.01) A61K 31/44 (2006.01) C07D 211/90 (2006.01)

Patent

CA 2031937

The four stereoisomers are disclosed having the formula: Image in which the asymmetric centers a and b are the same or different. The compounds are derived from the (+) and (-) alcohols and the (+) and (-) dihydropyridines and have either the absolute R or S configuration. Also disclosed are pharmaceutical compositions comprising an effective amount of the compounds in a pharmaceutically acceptable carrier and methods for producing cardiotonic activity using the compositions.

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