C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/4725 (2006.01) A61K 31/497 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2661436
Disclosed are compounds and pharmaceutically acceptable salts of Formula (I), wherein R0, R5, R6, R7, n, Q1-Q5, Y, and X1-X3 are as defined herein. Compounds of Formula (I) are useful in the treatment of diseases and/or conditions related to cell proliferation, such as cancer, inflammation, arthritis, angiogenesis, or the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds.
La présente invention concerne des composés et sels pharmaceutiquement admis représentés par la Formule (I). Dans cette formule, R0, R5, R6, R7, n, Q1-Q5, Y et X1-X3 sont tels que définis dans la description. Ces composés conviennent au traitement d'affections et/ou d'états en rapport avec la prolifération cellulaire, comme le cancer, l'inflammation, l'arthrite, l'angiogenèse ou analogue. L'invention concerne également des compositions pharmaceutiques comprenant les composés de l'invention, et des procédés pour le traitement de ces états au moyen de tels composés.
Barta Thomas
Huang Kenneth He
Ma Wei
Ommen Andy
Smith Emilie D.
Serenex Inc.
Smart & Biggar
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