Ketone derivatives and medical application thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 309/36 (2006.01) A61K 31/12 (2006.01) A61K 31/19 (2006.01) A61K 31/365 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61K 31/535 (2006.01) A61K 31/665 (2006.01) C07C 49/403 (2006.01) C07C 49/713 (2006.01) C07C 49/753 (2006.01) C07C 49/825 (2006.01) C07C 59/353 (2006.01) C07C 59/80 (2006.01) C07C 59/90 (2006.01) C07C 69/757 (2006.01) C07D 207/38 (2006.01) C07D 213/69 (2006.01) C07D 213/80 (2006.01) C07D 213/82 (2006.01) C07D 307/60 (2006.01) C07D 307/68 (2

Patent

CA 2222471

Ketone derivatives represented by general formula (a) and medecines containing the same or pharmacologically acceptable salts thereof as the active ingredient, particularly a hematocyte increasing agent efficacious in curing or preventing hematopenia after cancer chemotherapy or radiation therapy by increasing the number of thrombocytes, leukocytes or erythrocytes.

Cette invention concerne des dérivés de cétone correspondant à la formule générale (a), ainsi que des médicaments qui contiennent ces composés, ou leurs sels acceptables sur le plan pharmacologique, en qualité d'ingrédient actif. Cette invention concerne plus particulièrement un agent augmentant la quantité d'hématocytes, lequel est efficace dans le traitement ou la prévention de l'appauvrissement sanguin suite à un traitement anticancéreux par chimiothérapie ou par rayonnements, et permet d'augmenter le nombre de thrombocytes, de leucocytes ou d'érythrocytes.

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