L-glutamic acid oxidase, its production, and its use

Details L-glutamic acid oxidase, its production, and its use L-glutamic acid oxidase, its production, and its use

C - Chemistry, Metallurgy

12

Q

195/123, 195/39,

C12Q 1/26 (2006.01) C12N 9/02 (2006.01) C12N 9/06 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 1208581

ABSTRACT OF THE DISCLOSURE The present invention consists of the L-glutamic acid oxidase which is an L-amino acid oxidase catalyz- ing the oxidative deamination of the .alpha.-amino group of L-glutamic acid in the presence of water and oxygen to form .alpha.-ketoglutaric acid, ammonia and hydrogen peroxide, and having a very high substrate specificity for L- glutamic acid substantially without acting on L-glutamine and L-histidine and also a high stability, a micro- biological method of production thereof, an analytical method for assay of L-glutamic acid in a sample to be analyzed by the use of this enzyme, a reagent for analysis to practice the analytical method, a kit for analysis comprising said reagent, and a biosensor employ- ing said enzyme.

431424

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