Labeled peptides, and processes and intermediates useful for...

Details Labeled peptides, and processes and intermediates useful for... Labeled peptides, and processes and intermediates useful for...

C - Chemistry, Metallurgy

07

K

C07K 14/00 (2006.01) A61K 38/00 (2006.01) C07K 1/107 (2006.01) C07K 1/13 (2006.01)

Patent

CA 2424158

The invention provides peptide synthons having protected functional groups that can be selectively deprotected and subsequently modified to attach a desired moiety (e.g. a functional molecule such as a biophysical probe). The invention also provides peptide conjugates prepared from such synthons, as well as methods and intermediates useful for preparing such synthons and such conjugates.

L'invention concerne des synthons de peptides comportant des groupes fonctionnels protégés pouvant être déprotégés sélectivement et modifiés par la suite pour lier un groupe fonctionnel souhaité (par ex. une molécule fonctionnelle telle qu'une sonde biophysique). L'invention concerne également des conjugués de peptides préparés à partir desdits synthons, ainsi que des procédés et des intermédiaires servant à la préparation de tels synthons et conjugués.

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