A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/04 (2006.01) A61K 49/00 (2006.01) A61K 49/10 (2006.01) A61K 49/14 (2006.01) A61K 51/08 (2006.01)
Patent
CA 2265945
A human leucocyte elastase (HLE) inhibitor labelled with a detector moiety where the inhibitor is synthetic and has a molecular weight of less than 2000, is useful for the diagnostic imaging of sites of inflammation or infection in vivo, for labelling leucocytes in vitro, or for radiotherapy of arthritis. The HLE inhibitor is preferably a .beta.-lactam or an azetidinone.
Inhibiteur d'élastase de leucocytes humains (HLE) marqué à l'aide d'une fraction de détection, qui est synthétique et possède un poids moléculaire inférieur à 2000. Ledit inhibiteur est utile pour l'imagerie diagnostique de sites d'inflammation ou d'infection in vivo, pour marquer des leucocytes in vitro ou pour la radiothérapie de l'arthrite. Ledit inhibiteur de HLE est de préférence un .beta.-lactame ou une azétidinone.
Barnes Karen Jane
Bower Gary Robert
Forster Alan Michael
Knox Peter
Mendizabal Marivi
Amersham International Plc
Ge Healthcare Limited
Kirby Eades Gale Baker
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