C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/444 (2006.01) A61P 7/02 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2726702
The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4-P-M-M4 or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
Han Wei
Koch Stephanie
Lam Patrick
Li Yun-Long
Orwat Michael
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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