Leptin assay

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/85 (2006.01) C07K 14/47 (2006.01) C07K 14/715 (2006.01) C12N 5/10 (2006.01) C12N 15/16 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2252443

A trans-activation assay for leptin is described. Leptin response elements are located proximal to a promoter, and the promoter region is operatively linked to a reporter gene. When leptin binds with the receptor, the reporter gene is transcribed.

Dosage de la leptine par transactivation. Les éléments de réponse à la leptine sont situés à proximité d'un promoteur, tandis que la région du promoteur est liée de manière fonctionnelle au gène reporter. Lorsque la leptine se lie au récepteur, le gène reporter est transcrit.

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