C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/85 (2006.01) C07K 14/47 (2006.01) C07K 14/715 (2006.01) C12N 5/10 (2006.01) C12N 15/16 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2252443
A trans-activation assay for leptin is described. Leptin response elements are located proximal to a promoter, and the promoter region is operatively linked to a reporter gene. When leptin binds with the receptor, the reporter gene is transcribed.
Dosage de la leptine par transactivation. Les éléments de réponse à la leptine sont situés à proximité d'un promoteur, tandis que la région du promoteur est liée de manière fonctionnelle au gène reporter. Lorsque la leptine se lie au récepteur, le gène reporter est transcrit.
Chen Fang
Cully Doris F.
Hess John W.
Qureshi Sajjad A.
Rosenblum Charles I.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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