Leucine-rich 3,1-s-.alpha..sub.2-glycoprotein, process for...

A - Human Necessities – 23 – J

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A23J 1/06 (2006.01) A61K 35/16 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/531 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1108534

LEUCINE-RICH 3,1-S-?2-GLYCOPROTEIN, PROCESS FOR ISOLATING IT AND ITS USE Abstract of the disclosure: New glycoprotein having the following properties: a sedimentation constant in the ultracentrifuge of 3.1 A ? 0.2; molecular weight 49,600 ? 4,000; electophoretic mobility in the range of the ?2-globulins of the human serum; iso-electric range pH 3.8 to 4.1; extinction coefficient E 1 cm, 280 nm = 1% 7.0 ? 0.2; content of about 77 ? 2% of ?-aminoacids with a proportion of 17 ? 2% of leucine and about 22% of carbohydrates; specific immunological reaction with antibodies directed against the glycoprotein; which can be isolated from human sera and which may be used for the preparation of antisera enabling the detection and determination of the glycoprotein in body fluids.

301837

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